The system sequences through Zernike modes to compensate for aberrations, with optimization processes sometimes completing in minutes, tailored for high-speed scanning (e.g., 133 Hz for ROI).
The system, likely utilizing a variant described as VAM_GS (possibly a reference to Volumetric Adaptive Microscopy/Gaussian Stacking or similar technique), focuses on maintaining high resolution across a large, non-flat area. VAM_GS.Qiao.2.var
The system produces large, dense 3D datasets requiring advanced denoising, sometimes utilizing "zero-shot learning" methods to process weak fluorescence signals without pre-training on existing data. Summary of Performance (2026) Capability Field of View Imaging Depth Spatial Range Volume Coverage Resolution Cellular resolution The system sequences through Zernike modes to compensate