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: Effects typically begin within 5–15 minutes and last for 2–5 hours. Common Uses

: Users report increased alertness, energy, talkativeness, and sociability.

Marketed under brands like MIT45 and OPMS , these products use an extraction process to pull active alkaloids—primarily and 7-hydroxymitragynine (7-OH) —from the leaf.

: Because the compounds are already isolated from the plant material, they enter the bloodstream much faster than whole-leaf products. Effects and Dual Nature