Grey's Anatomy S16e16 May 2026

Season 16, Episode 16 of Grey's Anatomy , titled serves as the official farewell to original cast member Justin Chambers , who played Dr. Alex Karev . The episode aired on March 5, 2020, and is one of the most controversial in the series' history due to how it handles Alex's departure. ✉️ The Core Format: Letters from Alex

He apologizes for leaving via a letter and reveals he is filing for divorce. He leaves her his shares in Grey Sloan Memorial Hospital. Grey's Anatomy s16e16

While the letters dominate the episode, a few other developments occur at Grey Sloan: Season 16, Episode 16 of Grey's Anatomy ,

After reading the letter and realizing her marriage is over, Jo heads back to work, determined to stay strong despite the heartbreak. 🗣️ Fan and Critic Reaction ✉️ The Core Format: Letters from Alex He

They make the life-altering decision to foster Joey , a teenager Bailey treated who had been living in the foster care system.

Rather than appearing in person, Alex’s exit is explained through four separate sent to his closest friends and family. These letters reveal that Alex has been in Kansas for several weeks and does not plan to return to Seattle.

He discovered that Izzie used the embryos they froze years ago when she had cancer.