Keep Charisma at 1. Speech can easily be leveled up manually without wasting precious S.P.E.C.I.A.L. points.
Take Educated . It grants extra skill points every single time you level up. fallout-3-game-of-the-year-edition
Take Comprehension . This doubles the skill points you receive from reading found skill books. Keep Charisma at 1
Start with 9 Intelligence. This maximizes your skill points per level up right from the beginning. fallout-3-game-of-the-year-edition