6. Crazy: Handful Of Nothin'

Facing the side effects of chemotherapy, Walt decides to take a more proactive and aggressive role in his drug business. He shaves his head for the first time in this episode, adopting the iconic bald look.

Originally aired on March 2, 2008, it is widely considered a pivotal turning point in the series where Walter White begins his transformation into his criminal alter-ego, . Key Plot Points 6. Crazy Handful of Nothin'

The title is a reference to a line from the 1967 film Cool Hand Luke . It carries a double meaning in the episode: Facing the side effects of chemotherapy, Walt decides

Walt wins a family poker game by bluffing with a "handful of nothing" against Hank. Facing the side effects of chemotherapy